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कंपनी समाचार :
- What does vaccine efficacy mean? - Biology Stack Exchange
In the last few weeks, Pfizer BionTech, Moderna and AstraZeneca have each released preliminary estimates of the efficacy of their SARS-COV-2 vaccines But what do their respective efficacy percenta
- biochemistry - The effect on the efficacy and potency of a non . . .
As you see this type of antagonist causes a decrease in efficacy, but no decrease in potency is observed But how does a non-competetive antagonist that binds to the active site affect the dose-response curve? Does it lead to both a decrease in efficacy and potency? Unfortunately, there is no figure in the book to answer my question
- What exactly does reverse use-dependence mean?
Reverse use dependence is the reduction of a drug's efficacy with the repeated use of the target This contrasts with ordinary use dependence, for instance with $\mathrm {Na}^+$ blocking local anaesthetics, where they exert more block after tissue use Reverse use dependence is particularly (but not exclusively) seen with channel blockers such as quinidine Quinidine is a $\mathrm {Na
- What is the difference between effective and efficient selection?
Efficacy and efficiency are not interchangeable as they have different meanings, albeit a subtle difference You could on the other hand us efficacy and effective as synonyms, though properly the synonym of efficacy is effectivness
- Why does evolution not make our life longer? - Biology Stack Exchange
The same late-life reduction in the efficacy of selection also slows the rate at which alleles increasing lifespan spread A third consideration is the disposable-soma model, a description by T Kirkwood of life-history trade-offs which might explain why aging and earlier death could be favoured
- What does 5 and 3 mean in DNA and RNA strands?
The 5' and 3' mean "five prime" and "three prime", which indicate the carbon numbers in the DNA's sugar backbone The 5' carbon has a phosphate group attached to it and the 3' carbon a hydroxyl (-OH) group This asymmetry gives a DNA strand a "direction" For example, DNA polymerase works in a 5' -> 3' direction, that is, it adds nucleotides to the 3' end of the molecule (the -OH group is not
- Does body temperature affect human lifespan? - Biology Stack Exchange
9 If a human body were somehow to be kept at a cold temperature (say 30C) for the entire life of the given individual And somehow the brain could be fooled into thinking that this 30C feels nice and warm Would that given individual live longer as a consequence? What effect does a tempreature have on lifespan?
- What does substrate mean? - Biology Stack Exchange
The review article [1] uses substrate to mean freely floating nutrietnts Also, searching for "substrate loading" or "substrate loading rate" or such (on Google scholar) gives examples of substrate as something that is fed to the biofilm
- Why is 70% ethanol preferred for aseptic techniques?
Note Dexter's answer provides experimental evidence for why 70% ethanol is used My answer is based on my experience and understanding and the concentration that I have used in the lab I would add that 70% was likely chosen as a balance between cost and effectiveness If you are a little off on mixing the solution from 95% Ethanol stock, then you are still at a bactericidal level, where as if
- What is an ex vivo experiment? - Biology Stack Exchange
The terminologies are there to be helpful shorthands, i e they are not mutually exclusive terms and are not strictly defined jargon Case 1 is in vivo, the rest are not Concerning Case 2, removing the environment of a neuron cannot guarantee its native state as it exists in the organism, so it is not an in vivo experiment (at least not to most electrophysiologists) In vitro is just a
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